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This is the big one—a sporting event that often proves to be as much a life-changing experience as a physical challenge. Like all marathons, the NYC race covers 26.2 miles from start to finish—but no other city offers competitors the sights, sounds and sheer excitement of the New York City Marathon's five-borough course, which runs from Staten Island to Central Park. Thousands will run, millions will watch. For more information, visit nycmarathon.org.