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A favorite of the shoulder-pad-wearing crowd of the '80s, Anne Klein New York set up shop on the Upper East Side. Envisioned as "a metaphor for the modern woman," the boutique features smoked-glass shelves and travertine-marble floors and carries patent-leather and ostrich-skin handbags ($395--$795) crafted by Dominique Aurientis, a former accessories designer for chichi Italian label Salvatore Ferragamo.

Find more shops at Time Out New York.