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As leisurely as it may sound, fall-wardrobe shopping can prove stressful. Soho boutique Key, a women's clothing shop owned by stylist Mary Gasser and former public-relations maven Eve Gelade, aims to ease browsing anxiety with its homey decor, an outdoor patio and its can't-miss stock. Adorned with family knick-knacks and photos, the cheery space houses handpicked vintage pieces alongside up-and-coming--designer threads, including a Yim purple peacoat with crocheted buttons ($625), a Jak & Rae brown velvet short-sleeve jacket with mother-of-pearl buttons ($325), and an Amo & Bretti cashmere sweater with an asymmetrical hemline ($229)--which are poised to become your closet's key pieces this autumn.

Find more shops at Time Out New York.