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The Matthew Marks gallery was a driving force behind Chelseas transformation into an art destination, and it remains one of the neighborhoods biggest draws; its 9,000-square-foot, two-story locale has a second-floor public gallery. Marks showcases Nan Goldin, Andreas Gursky, Ellsworth Kelly, Willem de Kooning, Brice Marden and Ugo Rondinone.

Find more galleries & museums at Time Out New York.