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Spawned from the former San Domenico—a New York institution that embodied Central Park South’s formal opulence—SD26 fuses uptown sophistication with downtown cool to cater to a younger crowd of curious foodies. Its mod-Italian menu boasts an extensive selection of cured meats (from prosciutto to pork belly, with brief explanations of each), cheeses and innovative pasta and meat dishes (items such as garganelli with caviar or sweetbreads with coffee oil will remind you that you’re not in your neighborhood Italian joint). For those looking to try a bit of everything, most entrées are available in smaller—and less expensive—appetizer-size portions.