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Once, ship captains roamed South Street Seaport hawking exotic goods, but the former port of call has now officially gone to the dogs. Fortunately, this petcentric boutique, which caters to canines of all sizes as well as felines, throws a bone to their two-legged companions. The cozy spot features a salvaged fire hydrant; an in-house pooch (co-owner Amanda Byron Zink's enormous Great Dane); and a posh grooming spa adorned with 1950s subway tiles, barn wood from Connecticut and a slate tub from a stable in Maine. The regal treatment for four-legged creatures extends to Black Dog Farms custom-made raincoats, and bowwow treats such as organic frozen yogurt--which humans can eat too--and croissants in the "barkery."

Find more shops at Time Out New York.